Phosphate groups modifying myelin basic proteins are metabolically labile; methyl groups are stable.

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Phosphate groups modifying myelin basic proteins are metabolically labile; methyl groups are stable

Young and adult rats received intracranial injections of [33P]orthophosphoric acid. The time course of the appearance and decay of the radioactive label on basic proteins in isolated myelin was followed for 1 mo. Incorporation was maximal by 1 h, followed by a decay phase with a half-life of approximately 2 wk. However, radioactivity in the acid-soluble precursor pool (which always constituted ...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 1983

ISSN: 0021-9525,1540-8140

DOI: 10.1083/jcb.97.2.438